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Cruises from Colon, Panama

Cruises Out of Colon: Sailings & Itineraries

Jun, 27 2026
Caribbean Southern
Royal Caribbean International: Grandeur of the Seas
7 Nights
Starting from $144.96*/night ($1,014.72)*
Includes taxes and fees*
Jul, 04 2026
Caribbean Southern
Royal Caribbean International: Grandeur of the Seas
7 Nights
Starting from $158.01*/night ($1,106.05)*
Includes taxes and fees*
Jan, 02 2027
Caribbean Southern
Royal Caribbean International: Grandeur of the Seas
7 Nights
Starting from $164.16*/night ($1,149.14)*
Includes taxes and fees*
Jan, 09 2027
Caribbean Southern
Royal Caribbean International: Grandeur of the Seas
7 Nights
Starting from $174.13*/night ($1,218.92)*
Includes taxes and fees*
Jul, 11 2026
Caribbean Southern
Royal Caribbean International: Grandeur of the Seas
7 Nights
Starting from $160.86*/night ($1,126.05)*
Includes taxes and fees*
Jul, 18 2026
Caribbean Southern
Royal Caribbean International: Grandeur of the Seas
7 Nights
Starting from $176.65*/night ($1,236.55)*
Includes taxes and fees*

Colon is Panama’s second-largest city located at the exit of the Panama Canal on the Atlantic Coast. it is the world's second-largest free trade zone. It is the departure point for cruises to destinations like South America, the Caribbean, the Bahamas, and the Mexican Riviera. It is ideally located for exploring the Panama Canal and its Gatun Locks and Miraflores. Colon is a beautiful town with natural landscape. From here Panama City is about hour drive and perfect for outdoor adventure people.

Cruise Lines Out of Colon

Cruising out of Colón feels straightforward. You’re right by the Panama Canal, so there’s always movement around the port. It’s not a huge, overwhelming place, which helps. You get through check-in without much hassle, and before long you’re onboard and heading toward warmer water.

Royal Caribbean

Royal Caribbean
Photo by Royal Caribbean

Royal Caribbean keeps things easy and upbeat from Colón. These cruises don’t try too hard. You get pool decks that stay busy in the afternoon, casual food spots that are always open, and shows that fill up quickly after dinner.

Most sailing is around a week, heading into the Caribbean with a mix of beach stops and sea days. Prices are usually reasonable, especially if you book early. It’s a good fit if you want something simple, social, and not overcomplicated.

Cruise Ships Departing from Colon

Ships sailing from Colón are built for easy Caribbean trips. You won’t find anything too extreme here. It’s more about comfort, a steady pace, and getting you from one island to the next without any fuss.

Grandeur of the Seas

Grandeur of the Seas
Photo by Royal Caribbean

Grandeur of the Seas has a bit of an old-school feel, and that works in its favor. You’re not dealing with huge crowds or trying to figure out a massive layout. Within a day, you already know your way around.

Afternoons usually settle into a rhythm. People by the pool, music playing in the background, and no real pressure to do anything. Cruises are typically 6 to 8 days, which makes it a good option if you just want a quick break that still feels complete.

Top Cruise Destinations from Colon

Colón is one of those ports where the destination starts almost right away. You leave, and soon enough the water shifts to that bright Caribbean blue. Most routes are built around easy island stops, so you don’t spend too long just sailing.

Caribbean

This is the route most people take when they think of cruising. You leave Colón and within a day or two you’re stepping onto soft sand with water that’s clear enough to see straight to the bottom. Places like Cozumel or Grand Cayman show up often, and each stop has its own pace. In Cozumel, you’re likely in the water, snorkeling or diving. In Grand Cayman, it’s more about slowing down, maybe walking Seven Mile Beach and stopping for something local to eat. Cruises are usually 6 to 8 days, which keeps things simple. Prices are also more accessible, so it’s an easy choice without feeling basic.

Southern Caribbean

Head a bit further out and things feel more spaced out. The Southern Caribbean isn’t as busy, and the islands have more room to breathe. These cruises run longer, usually 8 to 12 days, since you’re covering more ground. The weather stays steady most of the year, which makes planning easier. Prices are a bit higher, but you get more time, more variety, and a pace that feels less rushed.

Colon Shore Excursions & Things to do

  • View the new locks at the Agua Clara Visitor Center for close-up views of ships.
  • Visit the historic forts of UNESCO World Heritage site like Fort San Lorenzo and Fort Sherman.
  • Take a boat tour on Gatun Lake to enjoy nature and wildlife or explore Gamboa Rainforest.
  • Go on a shopping spree to Colon Free Zone. It is the second largest free-trade zone in the world.
  • Go for a beach day at Playa Langosta or to Isla Grande.

Colon Cruises Tips & Tricks

Here in this section, you will get all kinds of blogs related to cruises from Colon, Panama including the tips & tricks. It has all information about colon cruise departure port, things to do, and sightseeing excursions.

FAQs related to Cruises From Colon

What cruise lines leave from Colon?

Royal Caribbean is the cruise line that leave from Colon, Panama.

What cruise ships leave from Colon?

Grandeur of the Seas is the cruise ship that departs from Colon, Panama.

What destinations can you cruise to from Colon?

Caribbean and Southern Caribbean

What is the Colon cruise terminal called?

The main cruise terminal in Colón, Panama, is called Colón 2000.