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22 Night Cruises

Cruises for 22 Nights

Find the best 22-night cruise on your budget and book your unforgettable vacation today. Here you will find amazing 22-nights cruise trips around the year. Discover a wide selection of itineraries, ships, and cruise lines for your 22-nights getaway. Whether you seek a family cruise or an adult-only retreat, book now on CruiseBooking.com for an unforgettable experience.

120 Itineraries Found
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22 Nights | Transatlantic | MSC Cruises | MSC Seaside

22 Nights | Transatlantic | MSC Cruises | MSC Seaside

MSC Seaside virtual-360

Genoa Miami

22 Nights

Genoa | Civitavecchia (Rome) | Palermo | Barcelona | Valencia | Cadiz | Santa Cruz de Tenerife | Barbados (Bridgetown) | St George's | San Juan | Miami **

Cruise Deals from Genoa to Miami

Lowest Rate*
  • Interior $559.00
  • Oceanview $909.00
  • Balcony $1,159.00
  • Suite $2,179.00
From $559.00* $25.41 / night(s)

22 Nights | Transatlantic | MSC Cruises | MSC Magnifica

22 Nights | Transatlantic | MSC Cruises | MSC Magnifica

MSC Magnifica virtual-360

Miami Civitavecchia (Rome)

22 Nights

Miami | RDTN | St. Johns | St Maarten (Philipsburg) | Fort de France | Barbados (Bridgetown) | Funchal | Lisbon | Alicante | Valencia | Barcelona | Civitavecchia (Rome) **

Cruise Deals from Miami to Civitavecchia (Rome)

Lowest Rate*
  • Interior $829.00
  • Oceanview $969.00
  • Balcony $1,199.00
  • Suite $3,679.00
From $829.00* $37.68 / night(s)

22 Nights | Transatlantic | MSC Cruises | MSC Divina

22 Nights | Transatlantic | MSC Cruises | MSC Divina

MSC Divina virtual-360

Genoa Miami

22 Nights

Genoa | Marseille | Barcelona | Valencia | Alicante | Lisbon | Funchal | St. Johns | St Maarten (Philipsburg) | San Juan | Miami | Nassau | Miami **

Cruise Deals from Genoa to Miami

Lowest Rate*
  • Interior $1,059.00
  • Oceanview $1,349.00
  • Balcony $1,639.00
  • Suite $6,179.00
From $1,059.00* $48.14 / night(s)

22 Nights | South America | MSC Cruises | MSC Poesia

22 Nights | South America | MSC Cruises | MSC Poesia

MSC Poesia virtual-360

Buenos Aires Southampton

22 Nights

Buenos Aires | Montevideo | Rio De Janeiro | Ilheus | Salvador | Fortaleza | Las Palmas | Funchal | Leixoes | La Coruna | Bilbao | Southampton **

Cruise Deals from Buenos Aires to Southampton

Lowest Rate*
  • Interior $1,129.00
From $1,129.00* $51.32 / night(s)

22 Nights | South America | MSC Cruises | MSC Grandiosa

22 Nights | South America | MSC Cruises | MSC Grandiosa

MSC Grandiosa virtual-360

Santos Civitavecchia (Rome)

22 Nights

Santos | Rio De Janeiro | Buzios | Salvador | Maceio | Las Palmas | Arrecifes | TNG | Malaga | Valencia | Marseille | Genoa | Civitavecchia (Rome) **

Cruise Deals from Santos to Civitavecchia (Rome)

Lowest Rate*
  • Interior $1,139.00
  • Oceanview $1,659.00
  • Balcony $2,159.00
  • Suite $4,379.00
From $1,139.00* $51.77 / night(s)

FAQs for 22 Night Cruises

All major cruise lines allow children on a 22-nights cruise trip across the ocean.

When choosing the best family cruise line for a 22-night cruise trip, a few options are known for their exceptional offerings and family-friendly experiences. Royal Caribbean International and Disney Cruise Line are two cruise lines that stand out.

When making a 22-night cruise trip memorable for teenagers, Royal Caribbean International is often considered an excellent choice. Royal Caribbean offers a range of amenities and activities specifically designed to engage and entertain teenagers, ensuring they have a fantastic time throughout the journey.
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