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22 Night Cruises

Cruises for 22 Nights

Find the best 22-night cruise on your budget and book your unforgettable vacation today. Here you will find amazing 22-nights cruise trips around the year. Discover a wide selection of itineraries, ships, and cruise lines for your 22-nights getaway. Whether you seek a family cruise or an adult-only retreat, book now on CruiseBooking.com for an unforgettable experience.

124 Itineraries Found
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22 Nights | Transatlantic | MSC Cruises | MSC Magnifica

22 Nights | Transatlantic | MSC Cruises | MSC Magnifica

MSC Magnifica

Miami Civitavecchia (Rome)

22 Nights
Miami | RDTN | St. Johns | St Maarten (Philipsburg) | Fort de France | Barbados (Bridgetown) | Funchal | Lisbon | Alicante | Valencia | Barcelona | Civitavecchia (Rome) **

Cruise Deals from Miami to Civitavecchia (Rome)

Lowest Rate*
  • Interior $739.00
  • Oceanview $989.00
  • Balcony $1,229.00
  • Suite $4,039.00
From $739.00* $33.59 / night(s)

22 Nights | Transatlantic | MSC Cruises | MSC Seaside

22 Nights | Transatlantic | MSC Cruises | MSC Seaside

MSC Seaside

Genoa Miami

22 Nights
Genoa | Civitavecchia (Rome) | Palermo | Barcelona | Valencia | Cadiz | Santa Cruz de Tenerife | Barbados (Bridgetown) | SGRG | San Juan | Miami **

Cruise Deals from Genoa to Miami

Lowest Rate*
  • Interior $929.00
  • Oceanview $1,199.00
  • Balcony $1,469.00
  • Suite $3,079.00
From $929.00* $42.23 / night(s)

22 Nights | South America | MSC Cruises | MSC Poesia

22 Nights | South America | MSC Cruises | MSC Poesia

MSC Poesia

Buenos Aires Southampton

22 Nights
Buenos Aires | Montevideo | Rio De Janeiro | Ilheus | Salvador | Maceio | Las Palmas | Funchal | Leixoes | La Coruna | Bilbao | Southampton **

Cruise Deals from Buenos Aires to Southampton

Lowest Rate*
  • Interior $999.00
  • Oceanview $1,339.00
  • Balcony $1,679.00
From $999.00* $45.41 / night(s)

22 Nights | Transatlantic | MSC Cruises | MSC Seaside

22 Nights | Transatlantic | MSC Cruises | MSC Seaside

MSC Seaside

Miami Marseille

22 Nights
Miami | St Maarten (Philipsburg) | St. Johns | Barbados (Bridgetown) | Funchal | Lisbon | Valencia | Palma De Mallorca | Palermo | Naples | Livorno | Marseille **

Cruise Deals from Miami to Marseille

Lowest Rate*
  • Interior $1,019.00
  • Oceanview $1,339.00
  • Balcony $1,659.00
  • Suite $3,079.00
From $1,019.00* $46.32 / night(s)

22 Nights | Europe | MSC Cruises | MSC Poesia

22 Nights | Europe | MSC Cruises | MSC Poesia

MSC Poesia

Genoa Montevideo

22 Nights
Genoa | Marseille | Tarragona | Valencia | Cadiz | Lisbon | Las Palmas | Santa Cruz de Tenerife | Recife | Salvador | Rio De Janeiro | Buenos Aires | Montevideo **

Cruise Deals from Genoa to Montevideo

Lowest Rate*
  • Oceanview $1,149.00
  • Balcony $1,419.00
From $1,149.00* $52.23 / night(s)

FAQs for 22 Night Cruises

All major cruise lines allow children on a 22-nights cruise trip across the ocean.

When choosing the best family cruise line for a 22-night cruise trip, a few options are known for their exceptional offerings and family-friendly experiences. Royal Caribbean International and Disney Cruise Line are two cruise lines that stand out.

When making a 22-night cruise trip memorable for teenagers, Royal Caribbean International is often considered an excellent choice. Royal Caribbean offers a range of amenities and activities specifically designed to engage and entertain teenagers, ensuring they have a fantastic time throughout the journey.
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