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  1. Cruise Booking
  2. By Length
  3. 21 Night Cruises

21 Night Cruises

Cruises for 21 Nights

Find the best 21-night cruise on your budget and book your unforgettable vacation today. Here you will find amazing 21-nights cruise trips around the year. Discover a wide selection of itineraries, ships, and cruise lines for your 21-nights getaway. Whether you seek a family cruise or an adult-only retreat, book now on CruiseBooking.com for an unforgettable experience.

549 Itineraries Found

*All prices are per person, in US Dollars, based on double occupancy.

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21 Nights | Transatlantic | MSC Cruises | MSC Seaside

21 Nights | Transatlantic | MSC Cruises | MSC Seaside
MSC Cruises

MSC Seaside

Livorno Miami

21 Nights
Livorno | Marseille | Barcelona | Valencia | Casablanca | Barbados (Bridgetown) | St George's | St Maarten (Philipsburg) | San Juan | Miami **

Cruise Deals from Livorno to Miami

Lowest Rate*
  • Interior $1,061.29*
  • Oceanview $1,301.29*
  • Balcony $1,551.29*
From USD $1,061.29* USD $50.54* / night(s) Includes taxes and fees*
What's Included?

21 Nights | Caribbean | Cunard | Queen Elizabeth

21 Nights | Caribbean | Cunard | Queen Elizabeth
Cunard

Queen Elizabeth

Miami Miami

21 Nights
Miami | Amber Cove | Montego Bay | Belize City | Cozumel | Miami | San Juan | St. Johns | St Lucia (castries) | Barbados (Bridgetown) | St Maarten (Philipsburg) | Road Town | Miami **

Cruise Deals from Miami
Lowest Rate*
  • Interior $1,256.00*
  • Oceanview $1,592.00*
  • Balcony $1,718.00*
  • Suite $5,141.00*
From USD $1,256.00* USD $59.81* / night(s) Includes taxes and fees*
What's Included?

21 Nights | Caribbean | Cunard | Queen Elizabeth

21 Nights | Caribbean | Cunard | Queen Elizabeth
Cunard

Queen Elizabeth

Miami Miami

21 Nights
Miami | San Juan | St. Johns | St Lucia (castries) | Barbados (Bridgetown) | St Maarten (Philipsburg) | Road Town | Miami | Amber Cove | Montego Bay | Belize City | Cozumel | Miami **

Cruise Deals from Miami
Lowest Rate*
  • Interior $1,266.00*
  • Oceanview $1,602.00*
  • Balcony $1,728.00*
  • Suite $5,151.00*
From USD $1,266.00* USD $60.29* / night(s) Includes taxes and fees*
What's Included?

21 Nights | Caribbean | Cunard | Queen Elizabeth

21 Nights | Caribbean | Cunard | Queen Elizabeth
Cunard

Queen Elizabeth

Miami Miami

21 Nights
Miami | Amber Cove | Montego Bay | Belize City | Cozumel | Miami | San Juan | St. Johns | St Lucia (castries) | Barbados (Bridgetown) | St Maarten (Philipsburg) | Road Town | Miami **

Cruise Deals from Miami
Lowest Rate*
  • Interior $1,295.00*
  • Oceanview $1,568.00*
  • Balcony $2,030.00*
  • Suite $7,280.00*
From USD $1,295.00* USD $61.67* / night(s) Includes taxes and fees*
What's Included?

21 Nights | Transatlantic | Princess | Regal Princess

21 Nights | Transatlantic | Princess | Regal Princess
Princess

Regal Princess

Southampton Galveston

21 Nights
Southampton | Le Havre | Bilbao | Vigo | Ponta Delgada | Antigua | St Thomas (Charlotte Amalie) | George Town, Grand Cayman Island | Galveston **

Cruise Deals from Southampton to Galveston

Lowest Rate*
  • Interior $1,302.00*
  • Balcony $1,542.00*
  • Suite $2,022.00*
From USD $1,302.00* USD $62.00* / night(s) Includes taxes and fees*
What's Included?

FAQs for 21 Night Cruises

The cost of a 21-night cruise with a family can vary depending on various factors such as cruise line, destination, cabin type, and amenities. Prices can range from a few thousand dollars to several tens of thousands of dollars.

The benefits of doing a 21-nights cruise trip are extensive exploration, relaxation and entertainment, an all-inclusive experience, a family-friendly atmosphere, and unpack once and visit multiple destinations.

When it comes to destinations for a 21-night cruise, there are numerous options. However, one suggestion for an enjoyable 21-night cruise could be a Mediterranean itinerary. This region offers a diverse mix of historical sites, stunning landscapes, and vibrant cultures. You can visit iconic cities like Barcelona, Rome, Athens, and Istanbul, explore picturesque islands such as Santorini and Mykonos, and experience the charm of lesser-known ports. The Mediterranean provides a perfect blend of history, culture, and natural beauty that can make a 21-night cruise truly memorable.