Discover exclusive cruise offers from our Travel Tuesday Cruise Deals
Find a cruise and book cruises direct - no booking fee!
  1. Cruise Booking
  2. By Length
  3. 21 Night Cruises

21 Night Cruises

Cruises for 21 Nights

Find the best 21-night cruise on your budget and book your unforgettable vacation today. Here you will find amazing 21-nights cruise trips around the year. Discover a wide selection of itineraries, ships, and cruise lines for your 21-nights getaway. Whether you seek a family cruise or an adult-only retreat, book now on CruiseBooking.com for an unforgettable experience.

Filter Your Search
Clear All

2024

* Availability & prices can change frequently, please continue with the booking to check latest availability & prices.
** Ports of Call may vary by departure date and subject to weather and other conditions.
404 Itineraries Found
  • Filters:

21 Nights | Europe | MSC Cruises | MSC Grandiosa

21 Nights | Europe | MSC Cruises | MSC Grandiosa

MSC Grandiosa

Santos Marseille

21 Nights

Cruise Deals from Santos to Marseille

Lowest Rate*
  • Interior $597.55
  • Oceanview $882.55
  • Balcony $1,110.55
  • Suite $2,906.05
From $597.55* $28.45 / night(s)

21 Nights | Middle East | MSC Cruises | MSC Opera

21 Nights | Middle East | MSC Cruises | MSC Opera

MSC Opera

Dubai Genoa

21 Nights

Cruise Deals from Dubai to Genoa

Lowest Rate*
  • Interior $609.00
  • Oceanview $1,089.00
  • Balcony $2,189.00
  • Suite $3,989.00
From $609.00* $29.00 / night(s)

21 Nights | Red Sea | MSC Cruises | MSC Virtuosa

21 Nights | Red Sea | MSC Cruises | MSC Virtuosa

MSC Virtuosa

Abu Dhabi Southampton

21 Nights

Cruise Deals from Abu Dhabi to Southampton

Lowest Rate*
  • Interior $689.00
  • Oceanview $989.00
  • Balcony $1,289.00
  • Suite $3,819.00
From $689.00* $32.81 / night(s)

21 Nights | Transatlantic | MSC Cruises | MSC Musica

21 Nights | Transatlantic | MSC Cruises | MSC Musica

MSC Musica

Buenos Aires Genoa

21 Nights

Cruise Deals from Buenos Aires to Genoa

Lowest Rate*
  • Interior $779.00
  • Oceanview $1,179.00
  • Balcony $1,479.00
  • Suite $3,729.00
From $779.00* $37.10 / night(s)

21 Nights | Transatlantic | MSC Cruises | MSC Seaside

21 Nights | Transatlantic | MSC Cruises | MSC Seaside

MSC Seaside

Civitavecchia (Rome) Miami

21 Nights

Cruise Deals from Civitavecchia (Rome) to Miami

Lowest Rate*
  • Interior $799.00
  • Oceanview $1,129.00
  • Balcony $1,459.00
  • Suite $2,939.00
From $799.00* $38.05 / night(s)

FAQs for 21 Night Cruises

The cost of a 21-night cruise with a family can vary depending on various factors such as cruise line, destination, cabin type, and amenities. Prices can range from a few thousand dollars to several tens of thousands of dollars.

The benefits of doing a 21-nights cruise trip are extensive exploration, relaxation and entertainment, an all-inclusive experience, a family-friendly atmosphere, and unpack once and visit multiple destinations.

When it comes to destinations for a 21-night cruise, there are numerous options. However, one suggestion for an enjoyable 21-night cruise could be a Mediterranean itinerary. This region offers a diverse mix of historical sites, stunning landscapes, and vibrant cultures. You can visit iconic cities like Barcelona, Rome, Athens, and Istanbul, explore picturesque islands such as Santorini and Mykonos, and experience the charm of lesser-known ports. The Mediterranean provides a perfect blend of history, culture, and natural beauty that can make a 21-night cruise truly memorable.
Cruise Inquiry