Discover Exclusive Offers and Special Deals on MSC Cruise Deals
Find a cruise and book cruises direct - no booking fee!
successmsg

errormsg

21 Night Cruises

Cruises for 21 Nights

Find the best 21-night cruise on your budget and book your unforgettable vacation today. Here you will find amazing 21-nights cruise trips around the year. Discover a wide selection of itineraries, ships, and cruise lines for your 21-nights getaway. Whether you seek a family cruise or an adult-only retreat, book now on CruiseBooking.com for an unforgettable experience.

449 Itineraries Found
  • Filters:

21 Nights | Transatlantic | Princess | Regal Princess

21 Nights | Transatlantic | Princess | Regal Princess

Regal Princess

Southampton Galveston

21 Nights

Southampton | Le Havre | Bilbao | Vigo | Funchal | Antigua | St Thomas (Charlotte Amalie) | George Town, Grand Cayman Island | Galveston **

Cruise Deals from Southampton to Galveston

Lowest Rate*
  • Interior $1,209.00
  • Balcony $2,087.00
From USD $1,209.00* USD $57.57 / night(s) Includes taxes and fees

21 Nights | Southern Europe | MSC Cruises | MSC Grandiosa

21 Nights | Southern Europe | MSC Cruises | MSC Grandiosa

MSC Grandiosa virtual-360

Rio De Janeiro Civitavecchia (Rome)

21 Nights

Rio De Janeiro | Buzios | Salvador | Maceio | Las Palmas | Arrecifes | TNG | Malaga | Valencia | Marseille | Genoa | Civitavecchia (Rome) **

Cruise Deals from Rio De Janeiro to Civitavecchia (Rome)

Lowest Rate*
  • Interior $1,246.92
  • Oceanview $1,736.92
  • Balcony $2,226.92
  • Suite $8,606.92
From USD $1,246.92* USD $59.38 / night(s) Includes taxes and fees

21 Nights | Southern Europe | MSC Cruises | MSC Grandiosa

21 Nights | Southern Europe | MSC Cruises | MSC Grandiosa

MSC Grandiosa virtual-360

Santos Genoa

21 Nights

Santos | Rio De Janeiro | Buzios | Salvador | Maceio | Las Palmas | Arrecifes | TNG | Malaga | Valencia | Marseille | Genoa **

Cruise Deals from Santos to Genoa

Lowest Rate*
  • Interior $1,287.92
  • Oceanview $1,777.92
  • Balcony $2,267.92
  • Suite $4,397.92
From USD $1,287.92* USD $61.33 / night(s) Includes taxes and fees

21 Nights | Transatlantic | Princess | Regal Princess

21 Nights | Transatlantic | Princess | Regal Princess

Regal Princess

Southampton Galveston

21 Nights

Southampton | Le Havre | Bilbao | Vigo | Funchal | Antigua | St Thomas (Charlotte Amalie) | George Town, Grand Cayman Island | Galveston **

Cruise Deals from Southampton to Galveston

Lowest Rate*
  • Interior $1,318.00
  • Balcony $1,687.00
  • Suite $2,318.00
From USD $1,318.00* USD $62.76 / night(s) Includes taxes and fees

21 Nights | Southern Europe | MSC Cruises | MSC Grandiosa

21 Nights | Southern Europe | MSC Cruises | MSC Grandiosa

MSC Grandiosa virtual-360

Genoa Santos

21 Nights

Genoa | Marseille | Barcelona | Malaga | Funchal | Santa Cruz de Tenerife | Maceio | Salvador | Rio De Janeiro | Illhabela | Santos **

Cruise Deals from Genoa to Santos

Lowest Rate*
  • Interior $1,378.92
  • Oceanview $1,868.92
  • Balcony $2,358.92
  • Suite $5,418.92
From USD $1,378.92* USD $65.66 / night(s) Includes taxes and fees

FAQs for 21 Night Cruises

The cost of a 21-night cruise with a family can vary depending on various factors such as cruise line, destination, cabin type, and amenities. Prices can range from a few thousand dollars to several tens of thousands of dollars.

The benefits of doing a 21-nights cruise trip are extensive exploration, relaxation and entertainment, an all-inclusive experience, a family-friendly atmosphere, and unpack once and visit multiple destinations.

When it comes to destinations for a 21-night cruise, there are numerous options. However, one suggestion for an enjoyable 21-night cruise could be a Mediterranean itinerary. This region offers a diverse mix of historical sites, stunning landscapes, and vibrant cultures. You can visit iconic cities like Barcelona, Rome, Athens, and Istanbul, explore picturesque islands such as Santorini and Mykonos, and experience the charm of lesser-known ports. The Mediterranean provides a perfect blend of history, culture, and natural beauty that can make a 21-night cruise truly memorable.
Cruise Inquiry